Caspase 3 9664 Cell Signaling

CytoSelect Cell Viability and Cytotoxicity Assay

CBA-240 96 assays
EUR 470.4
Description: The CytoSelect Cell Viability and Cytotoxicity Assay Kit provides a simple format for monitoring cell viability via metabolic activity. Live cells are detected with either MTT (colorimetric detection) or Calcein AM (fluorometric detection). Dead cells are detected by EthD-1 reagent (fluorometric). All 3 detection reagents are included, along with Saponin (a cell death initiator). Prior to the assay, cells may be treated with compounds or agents that affect cell viability. This kit is suitable for eukaryotic cells, not yeast or bacteria.

Caspase Assay Laboratories manufactures the caspase 3 9664 cell signaling reagents distributed by Genprice. The Caspase 3 9664 Cell Signaling reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact caspase assay. Other Caspase products are available in stock. Specificity: Caspase Category: 3 Group: 9664 Cell

MTT Cell Proliferation and Cytotoxicity Assay Kit

500 tests
EUR 284.4

Cell Proliferation and Cytotoxicity MTT Assay Kit

100 Assays
EUR 198

Cell Proliferation and Cytotoxicity MTT Assay Kit

500 Assays
EUR 360

Cell Proliferation and Cytotoxicity MTT Assay Kit

5000 Assays
EUR 1485.6

MTT Cell Proliferation and Viability Assay Kit

1 kit
EUR 319.26
Description: MTT Cell Proliferation and Viability Assay Kit

MTT Cell Proliferation and Cytotoxicity Assay Kit

1000 Assays
EUR 228

MTT Cell Proliferation and Cytotoxicity Assay Kit

500 Assays
EUR 136

9664 Cell information

TGF/SMAD Signaling Pathway SBE Report Cell Line-HEK293

ABC-RC122D 1 vial Ask for price
Description: The SBE Reporter andndash; HEK293 Cell Line is designed for monitoring the activity of the TGF /SMAD signaling pathway. The transforming growth factor beta (TGF) signaling pathway is involved in a diverse range of cell processes such as differentiation, cell cycle arrest, and immune regulation. TGF signaling has been linked to cardiac disease, cancer, Alzheimerandrsquo;s and other human diseases. TGF proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to phosphorylation and activation of SMAD2 and SMAD3, which then form a complex with SMAD4. The SMAD complex then translocates to the nucleus and binds to the SMAD binding element (SBE) in the nucleus, leading to transcription and expression of TGF / SMAD responsive genes.

Cell Meterâ„¢ Beta-Arrestin Translocation GPCR Signaling Kit

36390-100Tests 100 Tests
EUR 781
Description: Virtually all G protein coupled receptors (GPCRs) rapidly undergo desensitization by a common pathway upon activation by ligand binding.

Cell Meterâ„¢ Beta-Arrestin Translocation GPCR Signaling Kit

36391-200Tests 200 Tests
EUR 989
Description: Virtually all G protein coupled receptors (GPCRs) rapidly undergo desensitization by a common pathway upon activation by ligand binding.

Notch Signaling Pathway Notch1/CSL Reporter - HEK293 Cell Line

60652 2 vials
EUR 2175
Description: The Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) alone with expression construct for Notch1 E (NOTCH1 that has a deletion of the entire extracellular domain) stably integrated into HEK293 cells. Inside the cells, the Notch1 E can be cleaved by γ-secretase. The active Notch1 NICD is released to nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter using a known inhibitor of the Notch signaling pathway.

Notch Signaling Pathway Notch1/CSL Report Cell Line-HEK293

ABC-RC123D 1 vial Ask for price
Description: The Notch CSL Reporter andndash; HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) alone with expression construct for Notch1 E (NOTCH1 that has a deletion of the entire extracellular domain) stably integrated into HEK293 cells. Inside the cells, the Notch1 E can be cleaved by andgamma;-secretase. The active Notch1 NICD is released to nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter using a known inhibitor of the Notch signaling pathway.

Human TGF/SMAD Signaling Pathway SBE Reporter - HEK293 Cell Line

ABC-RC0130 1 vial Ask for price
Description: Human TGF/SMAD Signaling Pathway SBE Reporter Cell Line is derived from HEK293. Application: • Monitor TGF signaling pathway activity.• Screen for activators or inhibitors of the TGF/SMAD signaling pathway.

CRE/CREB Reporter (Luc) - Jurkat Cell Line (cAMP/PKA Signaling Pathway)

79636 2 vials
EUR 1810
Description: The CRE/CREB Reporter (Luc) - Jurkat Cell Line contains a firefly luciferase gene under the control of multimerized cAMP response element (CRE) stably integrated into Jurkat cells. Elevation of the intracellular cAMP level activates cAMP response element binding protein (CREB) to bind CRE and induces the expression of luciferase. This cell line is validated for response to stimulation by Forskolin.

CRE/CREB Reporter (Luc) - HEK293 Cell Line (cAMP/PKA Signaling Pathway)

60515 2 vials
EUR 2070
Description: The cAMP/PKA Signaling Pathway CRE/CREB Reporter (Luc) - HEK293 Cell Line is designed for monitoring the activity of the cAMP/ PKA signaling pathway. The cAMP/PKA Signaling Pathway CRE/CREB Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of multimerized cAMP response element (CRE) stably integrated into HEK293 cells. Elevation of the intracellular cAMP level activates cAMP response element binding protein (CREB) to bind CRE and induces the expression of luciferase.

Human Notch Signaling Pathway Notch1/CSL Reporter Cell Line-HEK293

ABC-RC0116 1 vial Ask for price
Description: Human Notch Signaling Pathway Notch1/CSL Reporter Cell Line is derived from HEK293. Application: • Monitor Notch signaling pathway activity.• Screen for activators or inhibitors of the Notch signaling pathway.

Transfection Collection™ : CRE/CREB Transient Pack (cAMP/PKA Cell Signaling Pathway)

79267 500 rxns.
EUR 715
Description: The CRE/CREB Transient Pack is designed to provide the tools necessary for transiently transfecting and monitoring the activity of the cAMP/PKA signaling pathway in cultured cells. The kit contains transfection-ready vectors containing firefly luciferase as a cAMP/PKA pathway-responsive reporter and constitutively expressing Renilla luciferase as a transfection control. It also includes the Dual Luciferase detection reagents to detect both luciferase activities and specialized medium for growing and assaying HEK293 cells._x000D_The key to the CRE/CREB Transient Pack is the CRE/CREB luciferase reporter vector, which is a cAMP/PKA Cell Signaling Pathway-responsive reporter. This reporter contains the firefly luciferase gene under the control of multimerized cAMP response elements (CRE) located upstream of a minimal promoter. Elevation of the intracellular cAMP level activates cAMP response element binding protein (CREB) to bind CRE and induces the expression of luciferase._x000D_The CRE reporter is premixed with constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with the constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical to determining pathway-specific effects and background luciferase activity._x000D_Additionally, the pack includes cell culture medium (BPS Medium 1) that has been optimized for use with HEK293 cells*. BPS Medium 1 includes MEM medium, 10% fetal bovine serum, 1% non-essential amino acids, sodium pyruvate, and 1% Pen/Strep. Finally, the pack provides the Dual Luciferase (Firefly-Renilla) Assay System. These luciferase reagents provide highly sensitive, stable detection of firefly luciferase activity and Renilla luciferase activity. The dual luciferase reagents can be used directly in cells in growth medium, and can be detected with any luminometer; automated injectors are not required._x000D_* Other mammalian cell lines may also be used, but an alternate cell culture medium may be required for optimal cell growth.

Suppressor of cytokine signaling 3

AP87871 1mg
EUR 2640

Suppressor of cytokine signaling 3

AP87975 1mg
EUR 2640

Suppressor of cytokine signaling 3

AP88182 1mg
EUR 2640

Suppressor of cytokine signaling 3

AP88297 1mg
EUR 2640

Suppressor of cytokine signaling 3

AP88327 1mg
EUR 2640

Suppressor of cytokine signaling 3

AP79160 1mg
EUR 2640

TCF/LEF reporter-HEK293 cell line (Wnt Signaling Pathway, Lithium-Dependent)

60501 2 vials
EUR 2505
Description: The Wnt Signaling Pathway TCF/LEF Reporter (Luc) - HEK293 Cell Line is designed for monitoring the activity of the Wnt/b-catenin signaling pathway. The Wnt Signaling Pathway TCF/LEF Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of TCF/LEF responsive elements stably integrated into HEK293 cells. This cell line is validated for the response to the stimulation of mouse Wnt3a and to the treatment with an inhibitor of Wnt/b-catenin signaling pathway.